London, UK, May 4, 2007 - SkyePharma PLC (LSE: SKP; NASDAQ: SKYE) [profile] announced today that it will delist its American Depositary Shares (the ‘ADSs’), each representing the right to receive ten ordinary shares of ten pence each of SkyePharma, from The NASDAQ Stock Market and, pursuant to the newly-adopted Rule 12h-6(a) under the U.S. Securities Exchange Act of 1934 (the ‘Exchange Act’), deregister and terminate SkyePharma’s reporting obligations under Sections 13(a) and 15(d) of Exchange Act.
SkyePharma’s Board of Directors authorized this action based on its assessment that (a) continued compliance with the rules of the U.S. Securities Exchange Commission (’SEC’) and NASDAQ, in particular Section 404 of the Sarbanes-Oxley Act of 2002, would be expensive and burdensome for a company such as SkyePharma considering the limited benefits it might realise and (b) all investors in the Ordinary Shares and ADSs of SkyePharma are accorded protection by SkyePharma’s continued compliance with the rules of the London Stock Exchange, on which it will maintain its listing, the Combined Code and other U.K. regulations.
In accordance with SEC rules and the rules of NASDAQ, SkyePharma has provided written notice to NASDAQ of its intent to delist. SkyePharma intends to file a Form 25 with the SEC on May 14, 2007 to effect the delisting. The delisting will be effective ten days after filing the Form 25, unless the Form 25 is earlier withdrawn by SkyePharma. SkyePharma reserves the right to delay the filing of the Form 25 or withdraw the Form 25 for any reason prior to its effectiveness.
SkyePharma intends to file a Form 15F with the SEC to deregister and terminate its reporting obligations under Section 13(a) and 15(d) of the Exchange Act as soon as practicable following the later of the effectiveness of the delisting and the coming into force of new Rule 12h-6 on June 4, 2007. The deregistration will be effective 90 days after the filing, unless the Form 15F is earlier withdrawn by SkyePharma. SkyePharma reserves the right to delay the filing of the Form 15F or withdraw the Form 15F for any reason prior to its effectiveness.
SkyePharma has not arranged for the listing of its ADSs or ordinary shares on another national securities exchange or for the quotation of its ordinary shares in a quotation medium in the United States.
SkyePharma intends to maintain its American Depositary Receipt (ADR) facility relating to the ADSs with The Bank of New York. The ADSs will trade over-the-counter (OTC) in the United States.
Frank Condella, Chief Executive Officer, said: ‘The US remains a very important market for SkyePharma, both as a market for our products and for investors in our Company. However, the time and expense associated with maintaining a second listing in the US is not cost effective, given that the vast majority of our trading volume and liquidity is on the London Stock Exchange. This move will save costs and enable management to spend more time in developing the business.’

